The basic principles of scientific research from the great French physiologist whose contributions in the 19th century included the discovery of vasomotor nerves; nature of curare and other poisons in human body; more.

Most of us display a bias toward the near: we prefer pleasurable experiences to be in our near future and painful experiences to be in our distant future. We also display a bias toward the future: we prefer pleasurable experiences to be in our future and painful experiences to be in our past. While philosophers have tended to think that near bias is a rational defect, almost no one finds future bias objectionable. In this essay, we argue that this hybrid (...) position is untenable. We conclude that those who reject near bias should instead endorse complete temporal neutrality. (shrink)

In this paper I defend Max Weber's concept of political legitimacy as a standard for the moral evaluation of states. On this view, a state is legitimate when its subjects regard it as having a valid claim to exercise power and authority. Weber’s analysis of legitimacy is often assumed to be merely descriptive, but I argue that Weberian legitimacy has moral significance because it indicates that political stability has been secured on the basis of civic alignment. Stability on this basis (...) enables all the goods of peaceful cooperation with minimal state violence and intimidation, thereby guarding against alienation and tyranny. Furthermore, I argue, since Weberian legitimacy is empirically measurable in terms that avoid controversial value judgments, its adoption would bridge a longstanding divide between philosophers and social scientists. (shrink)

Preface.--Science, ideology, and world view.--Objectives and methods in intellectual history.--The Kuhnian paradigm and the Darwinian revolution in natural history.--Biology and social theory in the nineteenth century.--Darwin as a social evolutionist.--Darwinism as a world view.--From Huxley to Huxley.--Postscript.

This paper presents an overview of the key ethical questions of performing gene editing research on military service members. The recent technological advance in gene editing capabilities provided by CRISPR/Cas9 and their path towards first-in-human trials has reinvigorated the debate on human enhancement for non-medical purposes. Human performance optimization has long been a priority of military research in order to close the gap between the advancement of warfare and the limitations of human actors. In spite of this focus on temporary (...) performance improvement, biomedical enhancement is an extension of these endeavours and the ethical issues of such research should be considered. In this paper, we explore possible applications of CRISPR to military human gene editing research and how it could be specifically applied towards protection of service members against biological or chemical weapons. We analyse three normative areas including risk–benefit analysis, informed consent, and inequality of access as it relates to CRISPR applications for military research to help inform and provide considerations for military institutional review boards and policymakers. (shrink)

Schizophrenia is a severe mental illness affecting sense of identity. Autobiographical memory deficits observed in schizophrenia could contribute to this altered sense of identity. The ability to give a meaning to personally significant events is also critical for identity construction and self-coherence. Twenty-four patients with schizophrenia and 24 control participants were asked to recall five self-defining memories. We assessed meaning making in participants’ narratives and afterwards asked them explicitly to give a meaning to their memories . We found that both (...) spontaneous and cued meaning making were impaired in patients with schizophrenia. This impairment was correlated with executive dysfunctions and level of negative symptoms. Our results suggest that patients’ difficulties in drawing lessons about past experiences could contribute to explain the lack of coherence observed in their life trajectories and their impaired social adjustment abilities. Implications for psychotherapy are also discussed. (shrink)

This paper explores how image worship was conceptualized and represented by Chinese authors during the first four centuries of Buddhist presence in China. Previous scholarship has argued that image worship was initially seen in China as a distinctively Buddhist practice, so much so that Buddhism was even known to the Chinese as the “Religion of Images”. By examining the history of the interpretation of this term, the evolution of stories about sacred images, and the presentation of image worship in debates (...) about the compatibility of Buddhism with Chinese culture, I will argue that image worship was first seen as a distinctly Buddhist or non-Chinese practice only in the late fifth century. Ironically, image worship came to be seen or represented as “foreign” only long after it had already become part of most forms of Chinese religion. (shrink)

We present evidence from a pre-registered experiment indicating that a philosophical argument––a type of rational appeal––can persuade people to make charitable donations. The rational appeal we used follows Singer’s well-known “shallow pond” argument (1972), while incorporating an evolutionary debunking argument (Paxton, Ungar, & Greene 2012) against favoring nearby victims over distant ones. The effectiveness of this rational appeal did not differ significantly from that of a well-tested emotional appeal involving an image of a single child in need (Small, Loewenstein, (...) and Slovic 2007). This is a surprising result, given evidence that emotions are the primary drivers of moral action, a view that has been very influential in the work of development organizations. We did not find support for our pre-registered hypothesis that combining our rational and emotional appeals would have a significantly stronger effect than either appeal in isolation. However, our finding that both kinds of appeal can increase charitable donations is cause for optimism, especially concerning the potential efficacy of well-designed rational appeals. We consider the significance of these findings for moral psychology, ethics, and the work of organizations aiming to alleviate severe poverty. (shrink)

All else being equal, most of us typically prefer to have positive experiences in the future rather than the past and negative experiences in the past rather than the future. Recent empirical evidence tends not only to support the idea that people have these preferences, but further, that people tend to prefer more painful experiences in their past rather than fewer in their future (and mutatis mutandis for pleasant experiences). Are such preferences rationally permissible, or are they, as time-neutralists contend, (...) rationally impermissible? And what is it that grounds their having the normative status that they do have? We consider two sorts of arguments regarding the normative status of future-biased preferences. The first appeals to the supposed arbitrariness of these preferences, and the second appeals to their upshot. We evaluate these arguments in light of the recent empirical research on future-bias. (shrink)

The socially responsible investment industry (SRI) is slowly changing from a screening, avoidance paradigm to a comprehensive paradigm that seeks to affect corporate behavior. Credible rating systems are a key component of this sea change. Reliable and recognizable social and environmental metrics are critical to this progress. The Total Social Impact (TSI) rating approach is a new social metric scheme based on a comprehensive rating of stakeholder issues. This paper describes the evolution of SRI ratings and the role that TSI (...) hopes to play in affecting business behavior by promoting principled business leadership. (shrink)

Three times between 1640 and 1651, once at considerable length, Hobbes used and accepted, and then mocked, repudiated and discarded, the ancient/medieval term recta ratio/right reason. These repeated fluctuations in his thinking and rhetorical strategy occurred during the writing of his three major treatises on moral and political theory, one additional note on the term in De Cive, and an unpublished commentary on Thomas White's De Mundo. They are made obvious by his substitution of recta ratio for reason or natural (...) reason when recycling passages from Elements of the Law for use in De Cive, and by his subsequent reversal of that substitution when revising other passages in De Cive for use in Leviathan. Despite incorporating recta ratio as a structural element in De Cive, he finally reverted in Leviathan to regarding the term as a deceptive verbal construct, non-existent in rerum natura, and ridiculing its users and proponents. Right reason carried connotations linked to it in antiquity and in the Middle Ages, and Hobbes's reversals in his view and use of it, and his final dismissal of it, provide further evidence and justification for the now familiar modern claim that he was a herald of modernity. (shrink)

"A collection of essays that addresses philosophical aspects of the films of Quentin Tarantino, focusing on topics in ethics, aesthetics, metaphysics, language, and cultural identity"--Provided by publisher.

The concept of ‘information’ is central to our understanding of financial markets, both in theory and in practice. Analysing information is not only a critical part of the activities of many financial practitioners, but also plays a central role in the Efficient Market Hypothesis (EMH). The central claim of this paper is that different data can count as information in fi-nancial markets and that particular investors do not consider all of the available data. This suggests that firstly, saying the price (...) of a stock should be $X once a particular piece of information has been incorporated in the price is only justifiable if we know that this information really is relevant for other investors. Sec-ondly, the EMH is often tested by looking at market behaviour after the release of information; again, this is only justified if we know that other market participants share the view that this is information. The purpose of this chapter is to suggest that there are good reasons for thinking that we do not know this. Finally, this chapter also suggests that bubbles in financial markets are best understood in terms of salience of information, rather than irrationality. (shrink)

This chapter contains sections titled: Playing the Blues Defining the Blues Wittgenstein to the Rescue Good Blues, Bad Blues, Walking Dead Blues Notes.

European Journal of Philosophy, EarlyView.

Encounters in the Arts, Literature, and Philosophy focuses on chance and scripted encounters as sites of tensions and alliances where new forms, ideas, meanings, interpretations, and theories can emerge. By moving beyond the realm of traditional hermeneutics, Jérôme Brillaud and Virginie Greene have compiled a volume that vitally illustrates how reading encounters represented in artefacts, texts, and films is a vibrant and dynamic mode of encountering and interpreting. With contributions from esteemed academics such as Christie McDonald, Pierre Saint-Amand, Susan (...) Suleiman, and Jean-Jacques Nattiez, this book is a multidisciplinary collaboration between scholars from a range of disciplines including philosophy, literature, musicology and film studies. It uses examples chiefly from French culture and covers the Early Modern era to the twentieth century while providing a thorough and representative array of theoretical and hermeneutical approaches. (shrink)

Transposable elements (TEs) are powerful facilitators of genome evolution, and hence of phenotypic diversity as they can cause genetic changes of great magnitude and variety. TEs are ubiquitous and extremely ancient, and although harmful to some individuals, they can be very beneficial to lineages. TEs can build, sculpt, and reformat genomes by both active and passive means. Lineages with active TEs or with abundant homogeneous inactive populations of TEs that can act passively by causing ectopic recombination are potentially fecund, adaptable, (...) and taxonate readily. Conversely, taxa deficient in TEs or possessing heterogeneous populations of inactive TEs may be well adapted in their niche, but tend to prolonged stasis and may risk extinction by lacking the capacity to adapt to change, or diversify. Because of recurring intermittent waves of TE infestation, available data indicate a compatibility with punctuated equilibrium, in keeping with widely accepted interpretations of evidence from the fossil record. We propose a general and holistic synthesis on how the presence of TEs within genomes makes them flexible and dynamic, so that genomes themselves are powerful facilitators of their own evolution. (shrink)

Recent research in moral psychology highlights the role of emotion and intuition in moral judgment. In the wake of these findings, the role and significance of moral reasoning remain uncertain. In this article, we distinguish among different kinds of moral reasoning and review evidence suggesting that at least some kinds of moral reasoning play significant roles in moral judgment, including roles in abandoning moral intuitions in the absence of justifying reasons, applying both deontological and utilitarian moral principles, and counteracting automatic (...) tendencies toward bias that would otherwise dominate behavior. We argue that little is known about the psychology of moral reasoning and that it may yet prove to be a potent social force. (shrink)

Background There is considerable variation in the functionality of bioethical services in different institutions and countries for children in hospital, despite new challenges due to increasing technology supports for children with serious illness and medical complexity. We aimed to understand how bioethics services address bioethical concerns that are increasingly encountered in paediatric intensive care. Methods A qualitative descriptive design was used to describe clinician’s perspectives on the functionality of clinical bioethics services for paediatric intensive care units. Clinicians who were members (...) of formal or informal clinical bioethics groups, or who were closely involved with the process of working through ethically challenging decisions, were interviewed. Interviews took place online. Resulting transcripts were analysed using thematic analysis. Results From 33 interviews, we identified four themes that described the functionality of bioethics services when a child requires technology to sustain life: striving for consensus; the importance of guidelines; a structure that facilitates a time-sensitive and relevant response; and strong leadership and teamwork. Conclusions Clinical bioethics services have the potential to expand their role due to the challenges brought by advancing medical technology and the increasing options it brings for treatment. Further work is needed to identify where and how bioethics services can evolve and adapt to fully address the needs of the decision-makers in PICU. (shrink)

The financial crisis has led to calls for increased regulation of the financial sector. In many respects this is uncontroversial because increased regulation should promote the behaviours we want to see, while limiting the behaviours we do not. This article takes issue with the idea that regulation, and guidelines, promote ethical behaviour in the way that we want them to. Firstly, judgement is often required to implement guidelines and regulations, which allows room for unethical behaviour. Secondly, we want financial professionals (...) to behave ethically even when there are significant incentives not to; so, verifying compliance with regulations and guidelines when such incentives are absent isn’t a good gauge of the ethical status of financial professionals. -/- The example of the valuation of the assets (Net Asset Value) of hedge funds illustrates these issues well. There are many rules governing how NAVs should be calculated, and while we can verify that a fund is abiding by the rules, the ability to manipulate the NAV remains. Furthermore, the incentive to do so is often only present during a crisis (usually to understate losses). Therefore, verifying compliance during ‘normal’ times is of little help in judging whether a manager will behave ethically when we most need him to. I first argue that the gap between compliance with regulations and ethical behaviour is best filled by the adoption of a virtue ethics approach, as discussed by Spalding & Oddo (2011), and Graafland & van de Ven (2011). I then discuss the implications of adopting such an approach for the financial industry’s codes of conduct, such as the CFA Institute’s ‘Code of Ethics and Standards of Professional Conduct’. Adopting a virtue ethics perspective would require a significant change in the emphasis of such codes. (shrink)

Privacy is a critical challenge for corporate social responsibility in the mobile device ecosystem. Mobile application firms can collect granular and largely unregulated data about their consumers, and must make ethical decisions about how and whether to collect, store, and share these data. This paper conducts a discourse analysis of mobile application developer forums to discover when and how privacy conversations, as a representative of larger ethical debates, arise during development. It finds that online forums can be useful spaces for (...) ethical deliberations, as developers use these spaces to define, discuss, and justify their values. It also discovers that ethical discussions in mobile development are prompted by work practices which vary considerably between iOS and Android, today’s two major mobile platforms. For educators, regulators, and managers interested in encouraging more ethical discussion and deliberation in mobile development, these work practices provide a valuable point of entry. But while the triggers for privacy conversations are quite different between platforms, ultimately the justifications for privacy are similar. Developers for both platforms use moral and cautionary tales, moral evaluation, and instrumental and technical rationalization to justify and legitimize privacy as a value in mobile development. Understanding these three forms of justification for privacy is useful to educators, regulators, and managers who wish to promote ethical practices in mobile development. (shrink)

People seem to have pure time preferences about trade-offs concerning their own pleasures and pains, and such preferences contribute to estimates of people's individual time discount rate. Do pure time preferences also matter to interpersonal welfare trade-offs, including those concerning the welfare of future generations? Most importantly, should the intergenerational time discount rate include a pure time preference? Descriptivists claim that the intergenerational discount rate should reflect actual people's revealed preferences, and thus it should include a pure time preference. Prescriptivists (...) claim that the intergenerational discount rate should be based on moral analysis, and thus they (often) claim that the rate of pure time preference should be zero. I argue that regardless of which view is correct, a focus on pure time preference is misplaced. First, the most plausible interpretation of descriptive preferences for intergenerational trade-offs is that people are socially biased and not time biased. Second, social bias is superior to time bias as a prescriptive reason to discount the welfare of future people. Third, recent advances in measuring social bias as a social discount rate make social bias a viable replacement for time bias in economic analyses of intergenerational welfare trade-offs. (shrink)

Abstract: This paper argues that continua of both genetic and environmental manipulation give rise to cases in which it is indeterminate whether the non-identity problem arises. In clear non-identity cases, impersonal principles can underwrite intuitions of wrongdoing. In clear cases of ordinary personal harm, ordinary ethical thinking about personal compensation augments or supersedes impersonal considerations. Indeterminate cases raise a special problem because it is indeterminate whether personal ethical considerations apply. Might indeterminacy of identity preclude a determinate and ethically justified resolution (...) of personal compensation claims? A way is suggested in which to continue ethically substantive discussion despite indeterminacy. (shrink)

Stem cell therapies should be available to people of all ethnicities. However, most cells used in the clinic will probably come from lines of cells stored in stem cell banks, which may end up benefiting the majority group most. The solution is to seek additional funding, earmarked for lines that will benefit minorities and offered as a public expression of apology for past discrimination.

This article proceeds from the thesis proposed by Frantz Fanon that colonialism, specifically settler colonialism, is a world-destroying structure that the colonized witness as a “veritable apocalypse.” Settler colonialism is apocalyptic not only in the sense that it attempts to permanently destroy and make irretrievable various other Indigenous worlds and ways of being-in-the-world, but also in that it builds the settler colonial world in, on, and with Indigenous lands and bodies. I read Fanon as proposing that settler colonialism builds apocalyptic (...) worlds with the murdered worlds of the colonized and then forces the colonized to navigate and embrace these violent and traumatic landscapes, which I call terrortories. I argue this is directly connected to Fanon's revolutionary psychiatric work and practice to decolonize and disalienate colonial medical and psychiatric facilities as structures of disablement, which requires the abolition of settler colonialism altogether. (shrink)